Pancreatic Beta Cell in Health and Disease by Susumu Seino,Graeme I. Bell PDF

By Susumu Seino,Graeme I. Bell

ISBN-10: 4431754512

ISBN-13: 9784431754510

ISBN-10: 4431998373

ISBN-13: 9784431998372

The beta cells of the pancreatic islets of Langerhans are the single cells within the physique that produce and secrete insulin. This metabolic hormone performs a crucial position within the upkeep of glucose homeostasis, regulating glucose uptake in muscle and adipose tissue in addition to carbohydrate, fats, and protein metabolism in those tissues and the liver. This publication presents a complete updated assessment of the beta phone in future health and ailment. Chapters tackle the structure and pathology of standard and diabetic pancreatic islets; rules of beta-cell proliferation and demise; the opportunity of stem cells and extra-pancreatic tissues as beta-cell substitute remedies; insulin biosynthesis; legislation of insulin secretion together with metabolic regulate, ion channels, hole junctions, cyclic AMP, incretins, and exocytosis; improvement of novel imaging options; and genetic problems of the beta mobilephone. a prime goal of the booklet is to motivate scholars and younger easy and medical investigators to turn into actively taken with diabetes examine and the hunt for brand new methods to avoid and deal with diabetes.

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Pancreatic Beta Cell in Health and Disease by Susumu Seino,Graeme I. Bell


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