By Shufeng Zhou
ISBN-10: 1466597879
ISBN-13: 9781466597877
Cytochromes are proteins that catalyze electron move reactions of recognized metabolic pathways and are categorised in numerous superfamilies. The CYP, or P450, superfamily money owed for ninety% of the oxidative metabolism of medical medicines. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes approximately 25% of all drugs within the human liver. Cytochrome P450 2D6: constitution, functionality, rules, and Polymorphism stories the present wisdom of CYP2D6 in addition to the maturing physique of proof indicating its value to medical and pharmacological researchers and practitioners.
This booklet specializes in the serious function CYP2D6 performs within the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural components of the gene that govern the hugely variable metabolism of a few medicines in scientific use. It highlights the influence of the practical roles of CYP2D6 on scientific perform and drug improvement and likewise discusses implications for special medication, recommendations to prevent opposed drug reactions, and paths for destiny research.
Cytochrome P450 2D6 is a distinct, beneficial e-book targeting a unmarried yet immensely robust human gene. It presents the 1st unmarried resource of finished info on CYP2D6 that serves as a big reference for clinical, biomedical, pharmaceutical, and nursing researchers, practitioners, and students.
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Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism by Shufeng Zhou
by John
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